Welcome to Scientific and Educational Website on Human Longevity !
Unraveling  the  Secrets 
of  Human  Longevity

Please note that the URL for our website has changed. 
Please update your bookmarks for the new URL: http://longevity-science.org


Breaking News:

Read new published scientific article "Early-Life Predictors of Human Longevity"
(pdf file, 0.4MB, requires Adobe Acrobat)

Our new published findings:
"Early-Life Factors Modulating Lifespan" pp. 27-50
In: Rattan, S.I.S (Ed.). Modulating Aging and Longevity.
Kluwer Academic Publishers, 2003, 336 pp.
http://www.wkap.nl/prod/b/1-4020-1369-8
and  http://www.wkap.nl/prod/b/1-4020-1369-8?a=1


Reliability Theory Explains Human Aging and Longevity

Science's SAGE KE (SCIENCE of  AGING KNOWLEDGE ENVIRONMENT )
16 July 2003 issue; Vol. 2003, No. 28, pp. 1-10
For Press Release click here

For recent Interview with Broad Overview of the Aging Problem click here

See recent presentations
at the 10th Congress of the International Association of Biomedical Gerontology, Cambridge, UK, and listen to our talk there


Table of Contents:


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Who we are:
Dr. Leonid A. Gavrilov
Center on Aging
NORC/University of Chicago
1155 East 60th Street
Chicago, IL 60637-2745
Fax: (773) 256-6313
Phone: (773) 256-6359
E-mail:  email gavrilov
Brief Biographical Sketch,    NIH  Biosketch
Detailed Curriculum Vitae
Expertise Profile:  http://myprofile.cos.com/gavrilov
See also: Who'sWho in America - 2002, 2003
Statement of Research Interests
Interview


 Dr. Natalia S. Gavrilova
  Center on Aging
  NORC/University of Chicago
  1155 East 60th Street
  Chicago, IL 60637-2745
  Fax: (773) 256-6313
  Phone: (773) 256-6359
  E-mail:  email gavrilova
  Brief Biographical Sketch, NIH Biosketch
  Detailed  Curriculum Vitae
  Expertise Profile: http://myprofile.cos.com/gavrilova
  Statement of Research Interests
 
 


Our collaborators in Russia are:
Galina N. Evdokushkina , M.Sc.,  and  Dr. Victoria G. Semyonova .

We also maintain close scientific contacts with
Dr. Bruce A. Carnes   at the University of Oklahoma.
 


What  we  have  found  and  published:
 
 

The Most Intriguing of Our (About 100) Publications:

Download 
the Reprint (PDF) version of 
"Season of Birth and Human Longevity"



Our most important publications are:

 

Gavrilov L. A.  and  Gavrilova N. S.
"THE  BIOLOGY  OF  LIFE  SPAN"
NY: Harwood Academic Publishers, 1991, 385 pages
Cited by Encyclopedia Britannica as recommended reference
Table of Contents
Subject Index
References
Citation Record
Reviews of this book

Available at:

Amazon,    AddALL,    Routledge                                       
NetStoreUSA.com,    OpenGroup,     Barnes&Noble       

eCampus.comBiggerBooks.com,  Fetchbook






 



 

 
MUTATION LOAD  AND  HUMAN LONGEVITY
Mutation Research, 1997, 377: 61-62.
To download full text click here
PARENTAL AGE  AT  CONCEPTION  AND  OFFSPRING  LONGEVITY
Reviews in Clinical Gerontology , 1997, 7: 5-12.
To download full text click here
EVOLUTION,  MUTATIONS  AND  HUMAN LONGEVITY
Human Biology, 1998, 70: 799-804. 
To download full text (1.8 MB) click here
SEASON OF BIRTH  AND  HUMAN LONGEVITY
Journal of Anti-Aging Medicine, 1999, 2(4): 365-366.
To download full text click here
For Media coverage click here or  here
HUMAN LONGEVITY  AND  PARENTAL AGE  AT CONCEPTION
In: Sex and Longevity . Springer-Verlag, Berlin, 2000, pp.7-31.
To download full text click here
EPIDEMIOLOGY  OF  HUMAN LONGEVITY: 
THE  SEARCH  FOR  APPROPRIATE  METHODOLOGY
Journal of Anti-Aging Medicine, 2001, 4(1): 13-30.
To download full text click here
BIODEMOGRAPHIC STUDY  OF  FAMILIAL DETERMINANTS  OF  HUMAN LONGEVITY
Population: An English Selection, 2001, 13(1): 197-222.
To download full text click here
WHEN  DOES  HUMAN LONGEVITY  START?:
DEMARCATION  OF  THE  BOUNDARIES  FOR  HUMAN LONGEVITY
Journal of Anti-Aging Medicine, 2001, 4(2): 115-124. Abstract
To download full text click here

THE  RELIABILITY THEORY  OF  AGING  AND  LONGEVITY
Journal of Theoretical Biology, 2001, 213(4): 527-545.  Abstract
To download full text click here
For Press Release click here
For Media Coverage click here

EVOLUTIONARY THEORIES  OF  AGING  AND  LONGEVITY
TheScientificWorldJOURNAL, 2002, 2: 339-356. 
To download full text in pdf format click  here
To download full text in HTML format click  here

THE  QUEST  FOR  A GENERAL  THEORY  OF  AGING AND  LONGEVITY
Science's SAGE KE (SCIENCE of  AGING KNOWLEDGE ENVIRONMENT )
for 16 July 2003; Vol. 2003, No. 28
http://sageke.sciencemag.org
To download full text as pdf file click here
Abstract, full text

EARLY-LIFE  PREDICTORS  OF  HUMAN  LONGEVITY:
ANALYSIS  OF  THE  19TH  CENTURY  BIRTH  COHORTS

Annales de Demographie Historique, 2003, 2: 177-198.
To download full text click  here



For more detailed list of our published findings please click here

For more publications available for downloading please click here


Who  supported  our  studies:
We would like to acknowledge the financial support for our research work provided by:


We would also like to acknowledge the important moral support for our research work (strong letters of recommendation, encouraging published reviews of our work, etc.) provided by:

and other researchers, mentioned here

Finally, we would like to acknowledge stimulating working environment at the Center on Aging , NORC/University of Chicago that allows us to conduct our research.  We are particularly grateful to Linda J. Waite and William L. Parish for their support of our studies at the Center on Aging.

If  you  would  like  to  support  our  studies,  please  contact  us  at:

gavrilov[at]longevity-science.org

Useful Links  and  Resources:
 

"Biodemography of Human Mortality and Longevity"

For syllabus of this course please click here .



Why  do  we  believe  that  the  scientific  breakthrough  in  longevity  studies  is  possible
 

Short Answer:

Numerous studies demonstrate that many manifestations of aging can be postponed or even reversed, and that lifespan can be significantly extended in experimental animals.  Moreover, our own studies found remarkable plasticity of human longevity (see above), and suggest that there may be a significant potential for further extension of human lifespan.

Supporting citation from Nature (2000, vol.408, p.261):
"The field of ageing research has been completely transformed in the past decade. When single genes are changed, animals that should be old stay young.  In humans, these mutants would be analogous to a ninety year old who looks and feels forty-five.  On this basis we begin to think of ageing as a disease that can be cured, or at least postponed. The field of ageing is beginning to explode, because so many are so excited about the prospect of searching for -- and finding -- the causes of ageing, and maybe even the fountain of youth itself."
Cited from: Guarente, L., and Kenyon, C. (2000) Genetic pathways that regulate ageing in model organisms. Nature 408, 255-262.
 

Detailed Answer:
 

This part is under construction.  Meanwhile, click here
 

We believe that the prospects for life extension depend on our own behavior by the mechanism of self-fulfilling prophecy.

For example, if we convince ourselves and the public that nothing could be done and/or should be done with aging ("tampering with aging"), the outcome is clear.  On the other hand, commitment of this nation already made possible several fantastic projects in the past (like the flight to the Moon), so why should we consider this generation less capable to great achievements?

We believe that the main challenge for accomplishing the life extension revolution is the mobilization of the nation and public support  for relevant research projects. From this perspective, the recent attempts to discredit anti-aging research efforts and to present them as a kind of scientific porn should be taken very seriously and, in our opinion, these attempts should not to be endorsed.  Moreover, we suggest to establish the Anti-Aging Science Award in order to stimulate legitimate anti-aging scientific studies and public support for them.
 

Recommended Reading:

Scientific peer-reviewed Journal of Anti-Aging Medicine
    This journal has distinguished Editorial Board including researchers from the National Institute on Aging (Drs. Vilhelm Bohr, Mark Lane, and Donald Ingram,  some of them are also the authors in this journal): http://www.liebertpub.com/pagedisplay/editorialboard.asp?id=27
  The journal is indexed in the "Web of Science," "Current Contents/Clinical Medicine," "SciSearch," "Research Alert" and "Focus on Pharmacology."  More information about this journal is available at: http://www.catchword.com/titles/10945458.htm
    The journal is published by Mary Ann Liebert, Inc., a major New York Publisher of more than 40 scientific and medical journals:  http://www.liebertpub.com/
     Therefore, consider submitting your manuscripts to this journal and informing your librarian about it for possible subscription: http://www.liebertpub.com/recform.asp?pubID=27


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