![]() |
of Human Longevity |
Table of Contents:
Who we are:
Dr.
Leonid A. Gavrilov


Dr. Natalia S. Gavrilova
Center on Aging
NORC/University of Chicago
1155 East 60th Street
Chicago, IL 60637-2745
Fax: (773) 256-6313
Phone: (773) 256-6359
E-mail: 
Brief Biographical
Sketch,
NIH Biosketch
Detailed Curriculum
Vitae
Expertise Profile: http://myprofile.cos.com/gavrilova
Statement
of Research Interests
Our collaborators in Russia are:
Galina N. Evdokushkina , M.Sc., and Dr. Victoria G. Semyonova .We also maintain close scientific contacts with
Dr. Bruce A. Carnes at the University of Oklahoma.
What
we have found and published:

Available at:
Amazon,
AddALL,
Routledge
NetStoreUSA.com,
OpenGroup,
Barnes&Noble
eCampus.com,
BiggerBooks.com,
Fetchbook
MUTATION LOAD AND HUMAN LONGEVITY
Mutation Research, 1997, 377: 61-62.
To download full text click herePARENTAL AGE AT CONCEPTION AND OFFSPRING LONGEVITY
Reviews in Clinical Gerontology , 1997, 7: 5-12.
To download full text click hereEVOLUTION, MUTATIONS AND HUMAN LONGEVITY
Human Biology, 1998, 70: 799-804.
To download full text (1.8 MB) click hereSEASON OF BIRTH AND HUMAN LONGEVITY
Journal of Anti-Aging Medicine, 1999, 2(4): 365-366.
To download full text click here
For Media coverage click here or hereHUMAN LONGEVITY AND PARENTAL AGE AT CONCEPTION
In: Sex and Longevity . Springer-Verlag, Berlin, 2000, pp.7-31.
To download full text click hereEPIDEMIOLOGY OF HUMAN LONGEVITY:
THE SEARCH FOR APPROPRIATE METHODOLOGY
Journal of Anti-Aging Medicine, 2001, 4(1): 13-30.
To download full text click hereBIODEMOGRAPHIC STUDY OF FAMILIAL DETERMINANTS OF HUMAN LONGEVITY
Population: An English Selection, 2001, 13(1): 197-222.
To download full text click hereWHEN DOES HUMAN LONGEVITY START?:
DEMARCATION OF THE BOUNDARIES FOR HUMAN LONGEVITY
Journal of Anti-Aging Medicine, 2001, 4(2): 115-124. Abstract
To download full text click hereTHE RELIABILITY THEORY OF AGING AND LONGEVITY
Journal of Theoretical Biology, 2001, 213(4): 527-545. Abstract
To download full text click here
For Press Release click here
For Media Coverage click hereEVOLUTIONARY THEORIES OF AGING AND LONGEVITY
TheScientificWorldJOURNAL, 2002, 2: 339-356.
To download full text in pdf format click here
To download full text in HTML format click hereTHE QUEST FOR A GENERAL THEORY OF AGING AND LONGEVITY
Science's SAGE KE (SCIENCE of AGING KNOWLEDGE ENVIRONMENT )
for 16 July 2003; Vol. 2003, No. 28
http://sageke.sciencemag.org
To download full text as pdf file click here
Abstract, full text
EARLY-LIFE PREDICTORS OF HUMAN LONGEVITY:
ANALYSIS OF THE 19TH CENTURY BIRTH COHORTS
Annales de Demographie Historique, 2003, 2: 177-198.
To download full text click here
For more detailed list of our published findings please click hereFor more publications available for downloading please click here
Who supported our studies:We would like to acknowledge the financial support for our research work provided by:
- National Institute on Aging (3 NIA grants)
- International Science Foundation ('Soros Foundation', 4 research grants)
- European Union (INTAS grant )
- Civilian Research and Development Foundation (CRDF grant)
- People like you (private persons and organizations)
We would also like to
acknowledge
the important moral support for our research work (strong letters of
recommendation,
encouraging published reviews of our work, etc.) provided by:
Finally, we would like to acknowledge stimulating working environment at the Center on Aging , NORC/University of Chicago that allows us to conduct our research. We are particularly grateful to Linda J. Waite and William L. Parish for their support of our studies at the Center on Aging.
If you would like to support our studies, please contact us at:
For syllabus of this course please click here .
Center
for Population Economics
Studies on the role of
early-life
events in health outcomes later in life
ImAginE
European Research Project
on
Immunology and Ageing
SAGE
KE
Science of Aging Knowledge
Environment
SYSEV
Systems aging in biology,
cosmology,
creep of materials, and organized physical systems
Why
do
we believe that the scientific
breakthrough
in longevity studies is possible
Short Answer:
Numerous studies demonstrate that many manifestations of aging can be postponed or even reversed, and that lifespan can be significantly extended in experimental animals. Moreover, our own studies found remarkable plasticity of human longevity (see above), and suggest that there may be a significant potential for further extension of human lifespan.
Supporting citation from Nature
(2000, vol.408,
p.261):
"The field of ageing research has been
completely
transformed in the past decade. … When single genes are changed,
animals
that should be old stay young. In humans, these mutants would be
analogous to a ninety year old who looks and feels forty-five. On
this basis we begin to think of ageing as a disease that can be cured,
or at least postponed. … The field of ageing is beginning to explode,
because
so many are so excited about the prospect of searching for -- and
finding
-- the causes of ageing, and maybe even the fountain of youth itself."
Cited from: Guarente, L., and Kenyon, C. (2000)
Genetic
pathways that regulate ageing in model organisms. Nature 408,
255-262.
Detailed Answer:
This
part is under construction. Meanwhile, click here
We believe that the prospects for life extension depend on our own behavior by the mechanism of self-fulfilling prophecy.
For example, if we convince ourselves and the public that nothing could be done and/or should be done with aging ("tampering with aging"), the outcome is clear. On the other hand, commitment of this nation already made possible several fantastic projects in the past (like the flight to the Moon), so why should we consider this generation less capable to great achievements?
We believe that the main challenge for
accomplishing
the life extension revolution is the mobilization of the nation and
public
support for relevant research projects. From this perspective,
the
recent attempts to discredit anti-aging research efforts and to present
them as a kind of scientific porn should be taken very seriously and,
in
our opinion, these attempts should not to be endorsed. Moreover,
we suggest to establish the Anti-Aging
Science
Award in order to stimulate legitimate
anti-aging scientific studies and public support for them.
Recommended Reading:
Scientific peer-reviewed
Journal
of Anti-Aging Medicine
This journal has distinguished Editorial Board including
researchers from the National Institute on
Aging
(Drs. Vilhelm Bohr, Mark Lane, and Donald Ingram, some of them
are
also the authors in this journal): http://www.liebertpub.com/pagedisplay/editorialboard.asp?id=27
The journal is indexed in the "Web of
Science,"
"Current Contents/Clinical Medicine," "SciSearch," "Research Alert" and
"Focus on Pharmacology." More information about this journal is
available
at: http://www.catchword.com/titles/10945458.htm
The journal is published by
Mary
Ann Liebert, Inc., a major New York Publisher of more than 40
scientific
and medical journals: http://www.liebertpub.com/
Therefore, consider
submitting
your manuscripts to this journal and informing your librarian about it
for possible subscription: http://www.liebertpub.com/recform.asp?pubID=27
Number of visitors:
is the visitor count to our web site as of August 4, 2001